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The benchmark indices settled around 0.5 per cent lower weighed by metal and private bank stocks.The S&P BSE Sensex ended at 33,891, down 176 points while the broader Nifty50 index settled at 10,198, down 52 points.Among sectoral indices, the Nifty Bank index ended 0.6 per cent lower led by a fall in the shares of IndusInd Bank and ICICI Bank. The Nifty Metal index, too, settled 1.1 per cent lower weighed by Coal India. However, Nifty PSU Bank index rose for the second consecutive day, ending 2.5 per cent higher led by Union Bank of India and Canara Bank.In individual stocks, Bharat Petroleum Corporation (BPCL) ended around 4 per cent lower at Rs 265.65 on the BSE after the oil marketing company reported a 48.3 per cent decline in its net profit to Rs 12.1871 billion for the second quarter ended September 2018. Among other stocks, Reliance Industries (RIL) fell 2.7 per cent to Rs 1,058.90 on the BSE.

TOP GAINERS:TECHM,ZEEL,GAIL

MAJORLOOSERS: BPCL,LOC,CIPLA

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The S&P BSE Sensex ended at 36,542, down 110 points while the broader Nifty50 index settled at 11,054, down 14 points.Among sectoral indices, the Nifty FMCG index fell 1.5 per cent led by a fall in ITC and Hindustan Unilever. The Nifty IT index, on the other hand, settled 1.9 per cent lower weighed by Infosys and Tata Consultancy Services (TCS).
In key individual stocks, YES Bank rose 1.4 per cent to Rs 223 on the BSE. DHFL also rose nearly 1 per cent to Rs 303.20.
Investors will keenly watch US Fed meet outcome due later in the day for fresh cues in the markets. Shares of Biocon hit a new high of Rs 718 per share, up 2% on Wednesday, extending their 6% rally on Tuesday on the BSE in an otherwise subdued market after the company said the inspection of its drug substance manufacturing site at Bengaluru campus by the US health regulator has concluded without any observations.In past one year, the stock of biotechnology firm has zoomed 109% as compared to a 16% rise in the S&P BSE Sensex.